Quantum annealers like those from D-Wave Systems implement adiabatic quantum computing to solve optimization problems, but their analog nature and limited control functionalities present challenges to correcting or mitigating errors. As quantum computing advances towards applications, effective error suppression is an important research goal. We propose a new approach called replication based mitigation (RBM) based on parallel quantum annealing. In RBM, physical qubits representing the same logical qubit are dispersed across different copies of the problem embedded in the hardware. This mitigates hardware biases, is compatible with limited qubit connectivity in current annealers, and is suited for available noisy intermediate-scale quantum (NISQ) annealers. Our experimental analysis shows that RBM provides solution quality on par with previous methods while being compatible with a much wider range of hardware connectivity patterns. In comparisons against standard quantum annealing without error mitigation, RBM consistently improves the energies and ground state probabilities across parameterized problem sets.