High-dimensional entanglement in qudit states offers a promising pathway towards the realization of practical, large-scale quantum systems that are highly controllable. These systems can be leveraged for various applications, including advanced quantum information processing, secure communications, computation, and metrology. In this context, quantum frequency combs have a crucial role as they inherently support multiple modes in both temporal and frequency domains, while preserving a single spatial mode. The multiple temporal and frequency modes of quantum frequency combs facilitate the generation, characterization, and control of high-dimensional time-frequency entanglement in extensive quantum systems. In this review article, we provide an overview of recent technological advancements in high-dimensional energy-time entangled quantum frequency combs. We explore how these time-frequency qudits, achieved using scalable telecommunications-wavelength components, can empower the creation of large-scale quantum states. Advances in quantum frequency combs can unlock new capabilities and versatility for promising developments in quantum science and technology.