The interest in a system often resides in the interplay among different parameters governing its evolution. It is thus often required to access many of them at once for a complete description. Assessing how quantum enhancement in such multiparameter estimation can be achieved depends on understanding the many subtleties that come into play: establishing solid foundations is key to delivering future technology for this task. In this article we discuss the state of the art of quantum multiparameter estimation, with a particular emphasis on its theoretical tools, on application to imaging problems, and on the possible avenues towards the next developments.