Abstract
Quantum multiparameter estimation promises to extend quantum advantage to the simultaneous high-precision measurements of multiple physical quantities. However, realizing this capability in practical quantum sensors under realistic conditions remains challenging due to intrinsic system imperfections. Here, we experimentally demonstrate multiparameter estimation using a nitrogen-vacancy (NV) center in diamond, a widely adopted solid-state quantum sensor. Leveraging electronic-nuclear spin entanglement and optimized Bell state measurement at room temperature, we simultaneously estimate the amplitude, detuning, and phase of a microwave drive from a single measurement sequence. Despite practical constraints, our results achieve linear sensitivity scaling for all parameters with respect to interrogation time. This work bridges the gap between foundational quantum estimation theory and real-world quantum sensing, opening pathways toward enhanced multiparameter quantum sensors suitable for diverse scientific and technological applications.